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Weight Management: new natural solutions to support energy metabolism and fat absorption Weight Management: new natural solutions to support energy metabolism and fat absorption
Written by Team Pharma
16.03.2026

Weight Management: new natural solutions to support energy metabolism and fat absorption

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Weight Management: new natural solutions to support energy metabolism and fat absorption

Virgile Duclos

Sales & Product Manager Pharma

IMPAG France SARL

+33 3 83 48 98 05 E-mail LinkedIn

Weight management continues to be one of the most dynamic areas within functional nutrition, driven by the global increase in overweight individuals, an ageing population and increasingly sedentary lifestyles. In contrast to traditional approaches focused solely on calorie restriction, the market is evolving towards more comprehensive strategies that combine energy metabolism, digestion and long-term adherence.

In this context, cellular energy expenditure plays a key role. Mitochondria, responsible for energy production in the body, directly influence metabolism, physical endurance and energy balance. A decrease in their activity is associated with lower energy consumption and greater fat accumulation. Therefore, stimulating their function represents an innovative approach in weight management, healthy ageing and sports nutrition formulations.

Find the best solutions

OleaVita, a French clinically proven olive leaf extract rich in oleanolic acid and polyphenols, acts by activating the TGR5 receptor, leading to GLP-1 secretion and promoting mitochondrial biogenesis and activity, as well as increasing energy expenditure. 2 clinical studies and 1 preclinical study have shown improvements in weight control parameters, body composition and physical performance, positioning it as an effective solution to support energy metabolism naturally.

The fundamental cause of obesity and overweight is an energy imbalance between calories consumed and calories expended  with the accumulation of fat as a result. A metabolic disorder interrupts the body’s regular process of converting food to energy for cellular use. A reduction in mitochondrial activity and the subsequent decrease in energy expenditure contribute substantially to metabolic dysfunction in aging, insulin resistance and diabetes. Enhancing mitochondrial activity improve metabolic homeostasis.

At the same time, digestive mechanisms continue to be a key tool in weight control. Chitoblock™, a high-purity chitosan from Norway obtained from sustainable marine raw materials, acts locally in the digestive tract by binding dietary fats. These non-absorbable complexes are eliminated naturally, helping to reduce fat absorption within a balanced diet and active lifestyle. Its non-systemic mode of action provides an attractive safety profile for modern formulations.

The combination of metabolic and digestive strategies allows for the development of more comprehensive and effective weight management solutions. While mitochondrial support promotes greater energy expenditure and vitality, reduced fat absorption acts directly on the caloric load of the diet.

In addition, the market increasingly demands natural, traceable ingredients produced under high quality standards. Both OleaVita and Chitoblock™ meet these expectations through controlled manufacturing processes and a strong commitment to sustainability and transparency.

Integrating these approaches represents a new generation of weight management formulations tailored to current consumer needs.