Contact person
Emre Akgün
Sales & Product Manager Pharma
IMPAG Import GmbH
Women’s health is evolving beyond traditional hormone-focused solutions. Today, innovation in this field increasingly adopts a broader 360° perspective, integrating vascular longevity, hormonal transition, and emotional balance as interconnected pillars of female wellbeing.
Across life stages, from premenstrual syndrome (PMS) to perimenopause and menopause, vascular function plays a central yet often underestimated role. Endothelial health influences thermoregulation, inflammatory responses, fatigue, cognitive clarity, and overall vitality. Addressing these mechanisms provides a differentiated strategy that goes beyond simple hormonal modulation.
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At the core of this vascular-centered approach stands Pineol® Premium, a high-quality Maritime Pine bark extract (Pinus pinaster) sourced in the South West of France, rich in polyphenols and procyanidins (>80%). Backed by strong clinical documentation, Pine Bark extract has demonstrated efficacy at low daily dosages (60–75 mg/day), offering both formulation flexibility and cost efficiency.
Clinical studies have shown significant reduction of PMS-related discomfort at 60 mg/day. In perimenopausal and menopausal women, improvements have been observed in hot flashes, fatigue, sleep quality, mood, cognitive performance, and overall wellbeing. These benefits are closely linked to improved endothelial function and vascular regulation, positioning Pineol® Premium as a science-based alternative to purely hormone-driven solutions.
Beyond PMS and menopause, maritime pine bark extract has also shown promising results in inflammatory gynecological conditions such as endometriosis, where vascular and inflammatory mechanisms are central components of symptom management.
This strategy is further reinforced by BeGrape® Premium, a Grape seed extract carefully sourced in Champagne (France) standardized in oligomeric procyanidins (OPCs), known for supporting microcirculation, capillary integrity, and oxidative stress control, key factors during hormonal transition and skin aging.
Complementing the physiological dimension, Symbalm™, an organic lemon balm extract selected and sourced in Provence (France), targets emotional balance and sleep quality. Hormonal fluctuations often increase stress sensitivity and sleep disturbances, making stress modulation an essential component of a comprehensive Women’s Health formulation.
Together, Pineol® Premium, BeGrape® Premium, and Symbalm™ enable the development of multifactorial, natural, and clinically supported solutions addressing vascular health, inflammatory balance, oxidative stress, and emotional wellbeing.